Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | GPR183 | P32249 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662390 | 0.89 | PPARG (0.41) | PPARGNPBWR1CREBBPCA12CA1 | |
| SCHEMBL31662519 | 0.79 | CA12 (0.41) | NPBWR1CA12CA1CA2CA9 | |
| SCHEMBL31662290 | 0.78 | USP2 (0.39) | NPBWR1NPC1RAB9ASMN1; SMN2SCN9A | |
| SCHEMBL31662404 | 0.77 | SCN9A (0.40) | NPBWR1CA12CA1CA2CA9 | |
| SCHEMBL31662347 | 0.77 | LMNA (0.38) | CA12CA1CA2CA9SCN9A | |
| SCHEMBL31662527 | 0.74 | MAPT (0.41) | NPBWR1RAB9ASMN1; SMN2SCN9A | |
| SCHEMBL31662315 | 0.74 | MAPT (0.41) | NPBWR1RAB9ASMN1; SMN2SCN9A | |
| SCHEMBL31662262 | 0.73 | LMNA (0.46) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3490016 | 0.70 | PRKCI (0.57) | GSK3BCA12CA1CA2CA9 | |
| SCHEMBL31417661 | 0.70 | PRKCI (0.57) | GSK3BCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |