Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 17/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662136 | 0.93 | HRH3 (0.42) | HRH3SLC6A4SLC6A2SLC6A3CHRM2 | |
| SCHEMBL31662491 | 0.92 | HRH3 (0.42) | HRH3SLC6A4SLC6A2SLC6A3CHRM2 | |
| SCHEMBL31662185 | 0.83 | HRH3 (0.37) | HRH3SLC6A4SLC6A2SLC6A3CHRM2 | |
| SCHEMBL31662117 | 0.74 | GRM2 (0.35) | HRH3KDM4EALDH1A1 | |
| SCHEMBL31662149 | 0.74 | PRKAB2 (0.44) | HRH3KDM4EALDH1A1 | |
| SCHEMBL31661907 | 0.72 | CPT1A (0.34) | HRH3 | |
| SCHEMBL31662141 | 0.72 | CPT1A (0.34) | HRH3 | |
| SCHEMBL31661914 | 0.72 | CPT1A (0.34) | HRH3 | |
| SCHEMBL31662147 | 0.72 | CYP11B2 (0.39) | HRH3 | |
| SCHEMBL31662459 | 0.69 | TBXAS1 (0.40) | HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |