SCHEMBL31662710

SCHEMBL31662710

CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)N1CCN(c2ccc(CN3C(=O)C(Cl)=C(Cl)C3O)cc2N)CC1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.42
HRH2 P25021 1/20 0.41
HRH1 P35367 1/20 0.41
UCHL1 P09936 6/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
ALDH1A1 P00352 1/20 0.39
WNT3 P56703 2/20 0.36
SFRP1 Q8N474 2/20 0.36
USP30 Q70CQ3 1/20 0.36
LMNA P02545 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
NPC1 O15118 1/20 0.35
PREP P48147 1/20 0.35
GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31662853 0.90 MEN1 (0.42) HSD17B10HRH2HRH1UCHL1MEN1
SCHEMBL31662829 0.88 VEGFA (0.41) MEN1KMT2AALDH1A1LMNANPSR1
SCHEMBL31662897 0.81 ALDH1A1 (0.42) HSD17B10HRH2HRH1UCHL1MEN1
SCHEMBL31663029 0.78 CCR4 (0.38) HRH2HRH1KMT2A
SCHEMBL31662938 0.78 MC4R (0.34) LMNA
SCHEMBL31662870 0.77 P2RX7 (0.41) LMNANPSR1
SCHEMBL31663171 0.76 SMN1; SMN2 (0.41) MEN1KMT2ALMNANPSR1
SCHEMBL31662801 0.75 SMN1; SMN2 (0.53) MEN1KMT2AALDH1A1LMNANPSR1
SCHEMBL31662839 0.75 MC4R (0.37) KMT2AALDH1A1LMNANPSR1
SCHEMBL31662803 0.73 HTR1A (0.35) ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025147756-A1 VIRAL SENSITIZERS COMPOSITIONS, METHODS AND USES THEREOF OTTAWA HOSPITAL RESEARCH INSTITUTE (CA) 2025-07-17 WO disclosed