SCHEMBL31662801

SCHEMBL31662801

CC(C)(C)OC(=O)N1CCN(c2ccc(CN3C(=O)C(Cl)=C(Cl)C3O)cc2)CC1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.53
HTT P42858 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
DDB1 Q16531 1/20 0.50
CRBN Q96SW2 1/20 0.50
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
CYP2C19 P33261 1/20 0.49
MAPT P10636 3/20 0.49
LMNA P02545 2/20 0.49
ALDH1A1 P00352 1/20 0.49
GPR119 Q8TDV5 8/20 0.47
VEGFA P15692 1/20 0.45
EGLN1 Q9GZT9 1/20 0.45
TP53 P04637 1/20 0.44
TSHR P16473 1/20 0.44
NAMPT P43490 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31662878 0.86 SMN1; SMN2 (0.42) SMN1; SMN2HTTNPSR1DDB1CRBN
SCHEMBL31662829 0.86 VEGFA (0.41) SMN1; SMN2HTTNPSR1DDB1CRBN
SCHEMBL31662817 0.86 GPR119 (0.50) SMN1; SMN2DDB1CRBNGPR119VEGFA
SCHEMBL31662870 0.86 P2RX7 (0.41) SMN1; SMN2HTTNPSR1MAPTLMNA
SCHEMBL31663171 0.85 SMN1; SMN2 (0.41) SMN1; SMN2HTTNPSR1DDB1CRBN
SCHEMBL31663031 0.85 GFER (0.47) SMN1; SMN2HTTMEN1KMT2AMAPT
SCHEMBL31663040 0.81 ME2 (0.44) MEN1KMT2AMAPTLMNATP53
SCHEMBL31662699 0.78 GAA (0.39) SMN1; SMN2HTTNPSR1MEN1KMT2A
SCHEMBL31662883 0.78 GAA (0.38) SMN1; SMN2HTTMEN1KMT2AMAPT
SCHEMBL5573222 0.76 MAPT (0.76) SMN1; SMN2HTTNPSR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025147756-A1 VIRAL SENSITIZERS COMPOSITIONS, METHODS AND USES THEREOF OTTAWA HOSPITAL RESEARCH INSTITUTE (CA) 2025-07-17 WO disclosed