SCHEMBL31662790

SCHEMBL31662790

Nc1ccc(CN2C(=O)C(Cl)=C(Cl)C2O)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.38
HPGD P15428 2/20 0.38
GBA1 P04062 2/20 0.36
KDM4E B2RXH2 1/20 0.36
HKDC1 Q2TB90 1/20 0.36
ALDH1A1 P00352 3/20 0.35
MAPT P10636 1/20 0.33
ERCC5 P28715 1/20 0.33
ITGB3 P05106 1/20 0.33
ITGB1 P05556 1/20 0.33
ITGAV P06756 1/20 0.33
ITGA5 P08648 1/20 0.33
TP53 P04637 1/20 0.33
MDM2 Q00987 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33
GFER P55789 1/20 0.32
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24624436 0.85 CAPN1 (0.37) LMNAHPGDKDM4EHKDC1TP53
SCHEMBL24624434 0.84 MAPT (0.42) LMNAKDM4EHKDC1ALDH1A1MAPT
SCHEMBL17987976 0.83 KMT2A (0.47) LMNAHPGDKDM4EALDH1A1TP53
SCHEMBL31662786 0.82 CA1 (0.51)
SCHEMBL31662895 0.81 PTGS1 (0.47) KDM4EALDH1A1MAPTTDP1
SCHEMBL17962566 0.81 FAAH (0.45) LMNAHPGDKDM4EHKDC1TP53
SCHEMBL17962576 0.81 KDM4E (0.39) LMNAHPGDGBA1KDM4EHKDC1
SCHEMBL31662937 0.80 ALDH1A1 (0.40) HPGDKDM4EHKDC1ALDH1A1MAPT
SCHEMBL31662836 0.80 KDM4E (0.36) LMNAHPGDKDM4EHKDC1ALDH1A1
SCHEMBL17962583 0.79 MEN1 (0.44) LMNAGBA1KDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025147756-A1 VIRAL SENSITIZERS COMPOSITIONS, METHODS AND USES THEREOF OTTAWA HOSPITAL RESEARCH INSTITUTE (CA) 2025-07-17 WO disclosed