SCHEMBL31662895

SCHEMBL31662895

O=C(O)c1ccc(CN2C(=O)C(Cl)=C(Cl)C2O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.47
PTGS2 P35354 1/20 0.47
ALDH1A1 P00352 4/20 0.44
MEN1 O00255 2/20 0.44
POLB P06746 2/20 0.44
GAA P10253 2/20 0.44
MAPT P10636 2/20 0.44
THRB P10828 2/20 0.44
RECQL P46063 2/20 0.44
KMT2A Q03164 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
KDM4E B2RXH2 1/20 0.44
USP2 O75604 1/20 0.44
NR4A1 P22736 1/20 0.44
APEX1 P27695 1/20 0.44
APOBEC3A P31941 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
HIF1A Q16665 1/20 0.44
APOBEC3G Q9HC16 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24624436 0.83 CAPN1 (0.37) KDM4E
SCHEMBL17962566 0.82 FAAH (0.45) PTGS1MEN1GAAKMT2AKDM4E
SCHEMBL31662790 0.81 LMNA (0.38) ALDH1A1MAPTTDP1KDM4E
SCHEMBL24624434 0.81 MAPT (0.42) ALDH1A1MEN1POLBGAAMAPT
SCHEMBL17962576 0.78 KDM4E (0.39) ALDH1A1MEN1MAPTKMT2AKDM4E
SCHEMBL31662836 0.78 KDM4E (0.36) ALDH1A1MEN1MAPTTHRBRECQL
SCHEMBL17962619 0.78 KDM4E (0.56) ALDH1A1MEN1MAPTKMT2AKDM4E
SCHEMBL31662937 0.78 ALDH1A1 (0.40) ALDH1A1MEN1GAAMAPTKMT2A
SCHEMBL31662909 0.77 ALDH1A1 (0.48) ALDH1A1MEN1POLBMAPTKMT2A
SCHEMBL17962583 0.77 MEN1 (0.44) ALDH1A1MEN1POLBMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025147756-A1 VIRAL SENSITIZERS COMPOSITIONS, METHODS AND USES THEREOF OTTAWA HOSPITAL RESEARCH INSTITUTE (CA) 2025-07-17 WO disclosed