SCHEMBL31662786

SCHEMBL31662786

NS(=O)(=O)c1ccc(CN2C(=O)C(Cl)=C(Cl)C2O)cc1

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA1 P00915 20/20 0.51
CA2 P00918 20/20 0.51
CA9 Q16790 20/20 0.51
CA12 O43570 16/20 0.51
CA7 P43166 5/20 0.51
CA4 P22748 6/20 0.45
CA6 P23280 2/20 0.44
CA5A P35218 2/20 0.44
CA14 Q9ULX7 2/20 0.44
CA5B Q9Y2D0 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17962615 0.86 HCRTR1 (0.40) CA1CA2CA9CA12CA7
SCHEMBL31662790 0.82 LMNA (0.38)
SCHEMBL17987976 0.79 KMT2A (0.47)
SCHEMBL31662895 0.77 PTGS1 (0.47)
SCHEMBL17962566 0.77 FAAH (0.45)
SCHEMBL19164237 0.76 CA2 (0.44) CA1CA2CA9CA12CA7
SCHEMBL17962576 0.76 KDM4E (0.39)
SCHEMBL31662836 0.75 KDM4E (0.36)
SCHEMBL31662937 0.75 ALDH1A1 (0.40)
SCHEMBL17962619 0.75 KDM4E (0.56)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025147756-A1 VIRAL SENSITIZERS COMPOSITIONS, METHODS AND USES THEREOF OTTAWA HOSPITAL RESEARCH INSTITUTE (CA) 2025-07-17 WO disclosed