SCHEMBL31662817

SCHEMBL31662817

CC(C)(C)OC(=O)N1CCN(c2ccc(CN3C(=O)C(Cl)=C(Cl)C3O)cn2)CC1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 7/20 0.50
DDB1 Q16531 1/20 0.47
CRBN Q96SW2 1/20 0.47
WNT3A P56704 1/20 0.44
RET P07949 2/20 0.43
ADK P55263 1/20 0.43
CKS1B P61024 2/20 0.43
SKP1 P63208 2/20 0.43
SKP2 Q13309 2/20 0.43
PGK1 P00558 1/20 0.42
MAP4K4 O95819 1/20 0.41
VEGFA P15692 1/20 0.41
EGLN1 Q9GZT9 1/20 0.41
HPGD P15428 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TP53 P04637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31662801 0.86 SMN1; SMN2 (0.53) GPR119DDB1CRBNVEGFAEGLN1
SCHEMBL31662802 0.83 RAB9A (0.41) HPGDTP53
SCHEMBL31662829 0.81 VEGFA (0.41) GPR119DDB1CRBNMAP4K4VEGFA
SCHEMBL31662796 0.81 AOC3 (0.39)
SCHEMBL31662870 0.81 P2RX7 (0.41) VEGFAEGLN1SMN1; SMN2TP53
SCHEMBL31663171 0.80 SMN1; SMN2 (0.41) DDB1CRBNVEGFAEGLN1SMN1; SMN2
SCHEMBL31663179 0.79 TLR7 (0.39) GPR119DDB1CRBN
SCHEMBL31662784 0.79 GAA (0.43) WNT3A
SCHEMBL26759314 0.78 GPR119 (0.62) GPR119DDB1CRBNWNT3ARET
SCHEMBL31662843 0.77 GPR119 (0.61) GPR119DDB1CRBNWNT3ARET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025147756-A1 VIRAL SENSITIZERS COMPOSITIONS, METHODS AND USES THEREOF OTTAWA HOSPITAL RESEARCH INSTITUTE (CA) 2025-07-17 WO disclosed