Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL266745 | 0.84 | MPO (0.45) | DHFR | |
| SCHEMBL5598227 | 0.82 | PIN1 (0.40) | — | |
| SCHEMBL380792 | 0.82 | DHFR (0.67) | DHFR | |
| Hydrochloric Acid SCHEMBL8377343 | 0.81 | DHFR (0.65) | DHFR | |
| Water SCHEMBL28837029 | 0.81 | DHFR (0.65) | DHFR | |
| SCHEMBL5727329 | 0.79 | DHFR (0.49) | DHFR | |
| SCHEMBL5727148 | 0.79 | DHFR (0.55) | DHFR | |
| SCHEMBL5727145 | 0.79 | DHFR (0.49) | DHFR | |
| SCHEMBL5726544 | 0.79 | DHFR (0.49) | DHFR | |
| SCHEMBL30462085 | 0.78 | TKT (0.54) | DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151642-A1 | MODIFIED ELONGATION FACTOR P AND METHODS OF USE THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2025-07-17 | — | — | WO | disclosed |