Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662950 | 0.95 | ALOX15 (0.50) | ALOX15TSHRCASP1RAB9AMEN1 | |
| SCHEMBL28060611 | 0.79 | DRD1 (0.51) | RAB9AMEN1KMT2APTPN1PTPN2 | |
| SCHEMBL31662941 | 0.78 | NPC1 (0.50) | TSHRRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL31662821 | 0.77 | ENPP3 (0.44) | MEN1KMT2APTPN1PTPN2HSD17B1 | |
| SCHEMBL31663025 | 0.74 | ENPP3 (0.44) | TSHRMEN1KMT2APTPN1PTPN2 | |
| SCHEMBL31662933 | 0.73 | HPGDS (0.45) | MEN1KMT2ACYP1A2DRD1 | |
| SCHEMBL18280244 | 0.70 | ALOX15 (0.78) | ALOX15TSHRCASP1RAB9AMEN1 | |
| SCHEMBL75219 | 0.70 | ALOX15 (1.00) | ALOX15TSHRCASP1RAB9AMEN1 | |
| SCHEMBL10726923 | 0.70 | ALOX15 (1.00) | ALOX15TSHRCASP1RAB9AMEN1 | |
| SCHEMBL22466175 | 0.70 | PTPN1 (0.56) | ALOX15TSHRCASP1RAB9APTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149498-A1 | BENZYLPIPERIDINE DERIVATIVES AS TRP4 ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |