Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 5/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31663086 | 0.86 | GRIN2B (0.35) | GRIN2BGRIN1PDE4D | |
| SCHEMBL31662882 | 0.85 | DRD1 (0.40) | PDE4DPDE4APDE4BPDE4CPDE3B | |
| SCHEMBL31663072 | 0.83 | PDE4D (0.41) | PDE4DPDE5ADRD1 | |
| SCHEMBL31663302 | 0.81 | PHGDH (0.34) | GRIN2BGRIN1PDE4DPDE4APDE4B | |
| SCHEMBL31663238 | 0.78 | CHRNB2 (0.34) | GRIN2BPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL31663184 | 0.75 | PTGES (0.38) | GRIN2BGRIN1PDE4DMAP3K12 | |
| SCHEMBL31663278 | 0.73 | GRIN2B (0.37) | GRIN2BGRIN1 | |
| SCHEMBL31662943 | 0.72 | PDE4D (0.38) | PDE4DPDE4APDE4BPDE4CTP53 | |
| SCHEMBL31662955 | 0.71 | SMN1; SMN2 (0.38) | PDE4DPDE4APDE4BPDE4CPDE3B | |
| SCHEMBL31662923 | 0.69 | PDE4A (0.48) | GRIN2BKCNH2PDE4DPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149498-A1 | BENZYLPIPERIDINE DERIVATIVES AS TRP4 ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |