SCHEMBL31662947

SCHEMBL31662947

CN(C)c1cccc(CN2C(=O)C(Cl)=C(Cl)C2O)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 2/20 0.38
CNR1 P21554 1/20 0.38
HDAC6 Q9UBN7 1/20 0.37
KMT2A Q03164 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ALDH1A1 P00352 2/20 0.34
TSHR P16473 1/20 0.34
GAA P10253 1/20 0.34
ALOX15 P16050 1/20 0.34
CTSD P07339 2/20 0.33
BACE1 P56817 2/20 0.33
KDM4E B2RXH2 2/20 0.33
HKDC1 Q2TB90 1/20 0.33
HPGD P15428 1/20 0.33
GRIN1 Q05586 1/20 0.33
GRIN2B Q13224 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
MCHR1 Q99705 1/20 0.33
CHRM3 P20309 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31662937 0.85 ALDH1A1 (0.40) HDAC1HDAC6KMT2AALDH1A1TSHR
SCHEMBL17987976 0.80 KMT2A (0.47) KMT2AL3MBTL1ALDH1A1TSHRKDM4E
SCHEMBL31662697 0.80 BRD4 (0.38) KMT2AALDH1A1TSHRKDM4EHKDC1
SCHEMBL24624434 0.75 MAPT (0.42) KMT2AALDH1A1GAAKDM4EHKDC1
SCHEMBL31662810 0.74 HPGD (0.45) ALDH1A1TSHRGAAHPGDLMNA
SCHEMBL24624436 0.73 CAPN1 (0.37) KDM4EHKDC1HPGDLMNA
SCHEMBL17962566 0.72 FAAH (0.45) KMT2ATSHRGAAKDM4EHKDC1
SCHEMBL17962614 0.72 ALDH1A1 (0.49) KMT2AALDH1A1KDM4ELMNASMN1; SMN2
SCHEMBL31662790 0.72 LMNA (0.38) HDAC6ALDH1A1TSHRKDM4EHKDC1
SCHEMBL17962576 0.72 KDM4E (0.39) HDAC6KMT2AALDH1A1ALOX15KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025147756-A1 VIRAL SENSITIZERS COMPOSITIONS, METHODS AND USES THEREOF OTTAWA HOSPITAL RESEARCH INSTITUTE (CA) 2025-07-17 WO disclosed