SCHEMBL31662697

SCHEMBL31662697

CNc1cccc(CN2C(=O)C(Cl)=C(Cl)C2O)c1

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.38
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
LMNA P02545 2/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPT P10636 2/20 0.38
ACKR3 P25106 5/20 0.35
HPGD P15428 2/20 0.33
KDM4E B2RXH2 1/20 0.33
HKDC1 Q2TB90 1/20 0.33
TSHR P16473 1/20 0.33
S1PR1 P21453 2/20 0.32
YTHDC1 Q96MU7 1/20 0.32
FAAH O00519 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31662836 0.85 KDM4E (0.36) KMT2AMEN1LMNAALDH1A1MAPT
SCHEMBL17987976 0.80 KMT2A (0.47) KMT2AMEN1LMNAALDH1A1HPGD
SCHEMBL31662947 0.80 HDAC1 (0.38) KMT2ALMNAALDH1A1HPGDKDM4E
SCHEMBL24624434 0.75 MAPT (0.42) KMT2AMEN1LMNAALDH1A1MAPT
SCHEMBL31662725 0.74 HPGD (0.45) KMT2AMEN1LMNAALDH1A1MAPT
SCHEMBL31662909 0.74 ALDH1A1 (0.48) BRD4KMT2AMEN1ALDH1A1MAPT
SCHEMBL24624436 0.73 CAPN1 (0.37) LMNAHPGDKDM4EHKDC1
SCHEMBL17962566 0.72 FAAH (0.45) KMT2AMEN1LMNAHPGDKDM4E
SCHEMBL17962614 0.72 ALDH1A1 (0.49) KMT2AMEN1LMNAALDH1A1MAPT
SCHEMBL31662790 0.72 LMNA (0.38) LMNAALDH1A1MAPTHPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025147756-A1 VIRAL SENSITIZERS COMPOSITIONS, METHODS AND USES THEREOF OTTAWA HOSPITAL RESEARCH INSTITUTE (CA) 2025-07-17 WO disclosed