Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 9/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31663216 | 0.93 | MGLL (0.43) | MGLLKEAP1NFE2L2HSD11B1PROKR1 | |
| SCHEMBL3678140 | 0.84 | NFE2L2 (0.58) | MGLLKEAP1NFE2L2SLC9A1SLC9A2 | |
| SCHEMBL21893929 | 0.78 | KEAP1 (0.51) | MGLLKEAP1NFE2L2HSD11B1 | |
| SCHEMBL16488574 | 0.77 | KEAP1 (0.50) | MGLLKEAP1NFE2L2HTTHSD11B1 | |
| SCHEMBL28621366 | 0.77 | KEAP1 (0.50) | MGLLKEAP1NFE2L2HSD11B1 | |
| Potassium Ion SCHEMBL21818514 | 0.76 | MGLL (0.42) | MGLLKEAP1NFE2L2HSD11B1PROKR1 | |
| SCHEMBL20812233 | 0.75 | MGLL (0.38) | MGLLKEAP1NFE2L2 | |
| SCHEMBL16488569 | 0.74 | HSD11B1 (0.47) | MGLLHSD11B1 | |
| SCHEMBL4023990 | 0.74 | HTT (0.35) | HTTHSD11B1 | |
| SCHEMBL619113 | 0.74 | HTT (0.36) | MGLLHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149628-A1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |