Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 10/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662967 | 0.93 | MGLL (0.42) | MGLLHSD11B1PROKR1KEAP1NFE2L2 | |
| SCHEMBL21893929 | 0.85 | KEAP1 (0.51) | MGLLHSD11B1KEAP1NFE2L2 | |
| SCHEMBL28621366 | 0.84 | KEAP1 (0.50) | MGLLHSD11B1KEAP1NFE2L2 | |
| Potassium Ion SCHEMBL21818514 | 0.83 | MGLL (0.42) | MGLLHSD11B1PROKR1KEAP1NFE2L2 | |
| SCHEMBL16488574 | 0.81 | KEAP1 (0.50) | MGLLHSD11B1KEAP1NFE2L2 | |
| SCHEMBL3678140 | 0.78 | NFE2L2 (0.58) | MGLLKEAP1NFE2L2 | |
| SCHEMBL24656079 | 0.74 | TSHR (0.44) | MGLLHSD11B1 | |
| SCHEMBL16488573 | 0.74 | LMNA (0.54) | HSD11B1 | |
| SCHEMBL4023990 | 0.72 | HTT (0.35) | HSD11B1 | |
| SCHEMBL25528083 | 0.71 | ALDH1A1 (0.37) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149628-A1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |