Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 18/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 14/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31663278 | 0.87 | GRIN2B (0.37) | GRIN2BGRIN1 | |
| SCHEMBL31662999 | 0.86 | GRIN2B (0.35) | GRIN2BGRIN1PDE4D | |
| SCHEMBL31662882 | 0.83 | DRD1 (0.40) | PDE4D | |
| SCHEMBL31663072 | 0.81 | PDE4D (0.41) | PDE4D | |
| SCHEMBL31663302 | 0.80 | PHGDH (0.34) | GRIN2BGRIN1PDE4D | |
| SCHEMBL31662869 | 0.79 | GRIN2B (0.35) | GRIN2BGRIN1PDE4D | |
| SCHEMBL31663238 | 0.79 | CHRNB2 (0.34) | GRIN2BPDE4D | |
| SCHEMBL31663184 | 0.71 | PTGES (0.38) | GRIN2BGRIN1PDE4D | |
| SCHEMBL31662943 | 0.70 | PDE4D (0.38) | PDE4D | |
| SCHEMBL22770894 | 0.69 | GRIN1 (0.46) | GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149498-A1 | BENZYLPIPERIDINE DERIVATIVES AS TRP4 ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |