Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 3/20 | 0.44 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.44 |
| ▸ | SMO | Q99835 | 2/20 | 0.38 |
| ▸ | DRD1 | P21728 | 2/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662821 | 0.95 | ENPP3 (0.44) | ENPP3ENPP1SMODRD1HSD17B1 | |
| SCHEMBL28060611 | 0.79 | DRD1 (0.51) | DRD1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL31662941 | 0.78 | NPC1 (0.50) | MEN1KMT2AALDH1A1TP53CYP1A2 | |
| SCHEMBL31662950 | 0.77 | ALOX15 (0.50) | SMODRD1HSD17B1HSD17B2POLB | |
| SCHEMBL31663217 | 0.74 | ALOX15 (0.50) | SMODRD1HSD17B1HSD17B2MEN1 | |
| SCHEMBL31662882 | 0.74 | DRD1 (0.40) | DRD1POLBALDH1A1LMNATP53 | |
| SCHEMBL31663072 | 0.71 | PDE4D (0.41) | DRD1POLBPDE4D | |
| SCHEMBL31662983 | 0.71 | PDE4A (0.45) | DRD1POLBALDH1A1LMNATP53 | |
| SCHEMBL31662955 | 0.70 | SMN1; SMN2 (0.38) | DRD1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL3271684 | 0.70 | ENPP3 (0.72) | ENPP3ENPP1SMOHSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149498-A1 | BENZYLPIPERIDINE DERIVATIVES AS TRP4 ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |