Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.33 |
| ▸ | USP8 | P40818 | 1/20 | 0.32 |
| ▸ | USP7 | Q93009 | 1/20 | 0.32 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8490160 | 0.83 | LMNA (0.50) | LMNAALDH1A1SMN1; SMN2MEN1MAPT | |
| SCHEMBL1533157 | 0.78 | TSHR (0.46) | ALDH1A1NOTUMCA1CA2PDK2 | |
| SCHEMBL10052139 | 0.78 | MAOA (0.45) | LMNAALDH1A1SMN1; SMN2MEN1MAPT | |
| SCHEMBL12948003 | 0.76 | ALDH1A1 (0.45) | LMNAALDH1A1SMN1; SMN2MEN1MAPT | |
| SCHEMBL31663089 | 0.76 | LMNA (0.35) | LMNAALDH1A1SMN1; SMN2MEN1MAPT | |
| SCHEMBL3154087 | 0.72 | CA1 (0.39) | ALDH1A1NOTUMCA1CA2PDK2 | |
| SCHEMBL13361828 | 0.72 | TRPV4 (0.38) | ALDH1A1MEN1KMT2ASLC22A12USP8 | |
| SCHEMBL13096355 | 0.72 | LMNA (0.41) | LMNAALDH1A1SMN1; SMN2MEN1MAPT | |
| SCHEMBL13077768 | 0.72 | ALDH1A1 (0.37) | LMNAALDH1A1SMN1; SMN2MEN1MAPT | |
| SCHEMBL158537 | 0.72 | BCAT1 (0.49) | ALDH1A1NOTUMCA1CA2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951046-B2 | TRPA1 modulators | ALGOMEDIX, INC. (US) | 2018-04-24 | — | — | US | disclosed |