Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.32 |
| ▸ | DPP4 | P27487 | 3/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.32 |
| ▸ | NOTCH1 | P46531 | 2/20 | 0.31 |
| ▸ | RBPJ | Q06330 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | CTSG | P08311 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17321226 | 0.90 | CYP19A1 (0.38) | L3MBTL1CYP19A1MAPK1AADAT | |
| SCHEMBL31663492 | 0.90 | CYP19A1 (0.38) | L3MBTL1CYP19A1MAPK1AADAT | |
| Trifluoroacetic Acid SCHEMBL4803583 | 0.81 | RIPK1 (0.43) | RIPK1MAPK1 | |
| SCHEMBL18379150 | 0.78 | ALDH1A1 (0.40) | PTPN7MAPK1AADAT | |
| Trifluoroacetic Acid SCHEMBL15956777 | 0.76 | NR3C2 (0.39) | CYP19A1 | |
| SCHEMBL18368155 | 0.73 | BLM (0.37) | CYP19A1MAPK1AADAT | |
| SCHEMBL15964565 | 0.73 | CA2 (0.39) | DPP4MAPK1AADAT | |
| SCHEMBL12345907 | 0.73 | CYP19A1 (0.39) | CYP19A1RIPK1MAPK1 | |
| Trifluoroacetic Acid SCHEMBL17332759 | 0.72 | KIF11 (0.38) | KDM1ARIPK1AADAT | |
| Trifluoroacetic Acid SCHEMBL15565133 | 0.72 | KMT2A (0.39) | KDM1ACYP19A1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12365695-B2 | Fused ring heteroaryl compounds as RIPK1 inhibitors | BISICHEM CO., LTD. (KR) | 2025-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12365695-B2 | Fused ring heteroaryl compounds as RIPK1 inhibitors | RIPK1, RIPK3, RIPK4 | PTPN7 1776/4885L3MBTL1 2192/4885KDM1A 1962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.