SCHEMBL30584763

SCHEMBL30584763

Cc1ccc(CN2CCC(CNC(=O)C3CCN(c4nc(-c5ccc(C#N)cc5)no4)CC3)C2)nc1

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.45
▸ MEN1 O00255 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ LMNA P02545 2/20 0.41
▸ ACHE P22303 1/20 0.40
▸ CCR5 P51681 1/20 0.40
▸ CHRM4 P08173 4/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ NPC1 O15118 1/20 0.40
▸ ALDH1A1 P00352 1/20 0.40
▸ RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30584854 0.90 MAPT (0.47) MAPTMEN1KMT2ALMNACCR5
SCHEMBL30584823 0.90 ACHE (0.51) MAPTMEN1KMT2ALMNAACHE
SCHEMBL31667484 0.89 MEN1 (0.56) MAPTMEN1KMT2ALMNASMN1; SMN2
Formic Acid SCHEMBL31546359 0.86 MEN1 (0.54) MAPTMEN1KMT2ALMNASMN1; SMN2
SCHEMBL25434607 0.81 MAPT (0.47) MAPTMEN1KMT2ALMNACHRM4
SCHEMBL25434601 0.81 MAPT (0.47) MAPTMEN1KMT2ALMNACHRM4
SCHEMBL31546440 0.81 MEN1 (0.55) MAPTMEN1KMT2ALMNASMN1; SMN2
SCHEMBL30585036 0.81 MAPT (0.52) MAPTLMNAACHECCR5CHRM4
SCHEMBL25433137 0.80 CCR5 (0.53) MAPTMEN1KMT2ALMNACCR5
SCHEMBL30584949 0.79 MEN1 (0.49) MAPTMEN1KMT2ALMNACCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP claimed
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP disclosed
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 — — US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 — — US disclosed
EP-4463452-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2024-11-20 — — EP disclosed
WO-2023177700-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2023-09-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 MAPT 2999/4885MEN1 1569/4885KMT2A 1404/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 MAPT 2999/4885MEN1 1569/4885KMT2A 1404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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