Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | ATP4A | P20648 | 3/20 | 0.49 |
| ▸ | ATP4B | P51164 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | RARA | P10276 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.45 |
| ▸ | RARG | P13631 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26136461 | 0.85 | RARA (0.61) | ALOX5ATP4AATP4BKMT2ARARA | |
| SCHEMBL26134361 | 0.80 | ATP4A (0.52) | ALOX5ATP4AATP4BESR2RARA | |
| SCHEMBL26134852 | 0.78 | ATP4A (0.50) | ATP4AATP4BESR2RARARARB | |
| SCHEMBL2091654 | 0.75 | KDM1A (0.48) | KMT2AESR2ADORA3KDM1A | |
| SCHEMBL9954348 | 0.75 | PTGS1 (0.49) | KMT2AESR2ADORA3NPC1RAB9A | |
| SCHEMBL2089024 | 0.75 | KMT2A (0.64) | KMT2AESR2TRPM8ADORA3HRH3 | |
| SCHEMBL14064281 | 0.74 | KMT2A (0.47) | KMT2ATRPM8RARARARBRARG | |
| SCHEMBL31677707 | 0.73 | MAPT (0.72) | ALOX5ATP4AATP4BKMT2AESR2 | |
| SCHEMBL31678026 | 0.73 | MAPT (0.72) | ALOX5ATP4AATP4BKMT2AESR2 | |
| SCHEMBL26136626 | 0.73 | MAPT (0.72) | ALOX5ATP4AATP4BKMT2AESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250270199-A1 | THIAZOLE DERIVATIVES AND METHODS OF USING THE SAME | ARKANSAS STATE UNIV JONESBORO (US) | 2025-08-28 | — | — | US | claimed |
| US-20250270199-A1 | THIAZOLE DERIVATIVES AND METHODS OF USING THE SAME | ARKANSAS STATE UNIV JONESBORO (US) | 2025-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250270199-A1 | THIAZOLE DERIVATIVES AND METHODS OF USING THE SAME | TST, GOT2, TPMT | ALOX5 569/4885ATP4A 2515/4885ATP4B 3496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.