Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 3/20 | 0.52 |
| ▸ | ATP4B | P51164 | 3/20 | 0.52 |
| ▸ | SNCA | P37840 | 3/20 | 0.50 |
| ▸ | RARA | P10276 | 2/20 | 0.48 |
| ▸ | RARB | P10826 | 2/20 | 0.48 |
| ▸ | RARG | P13631 | 2/20 | 0.48 |
| ▸ | PLTP | P55058 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26136461 | 0.89 | RARA (0.61) | ATP4AATP4BSNCARARARARB | |
| SCHEMBL26134852 | 0.88 | ATP4A (0.50) | ATP4AATP4BSNCARARARARB | |
| SCHEMBL31677663 | 0.80 | ALOX5 (0.56) | ATP4AATP4BSNCARARARARB | |
| SCHEMBL11452930 | 0.77 | RARA (0.69) | ATP4AATP4BRARARARBRARG | |
| SCHEMBL28672395 | 0.74 | SMN1; SMN2 (0.46) | ATP4AATP4BRARARARBRARG | |
| SCHEMBL26136213 | 0.72 | KDM4E (0.68) | MAPTPOLBKDM4EALDH1A1GAA | |
| SCHEMBL26125672 | 0.72 | ALOX5 (0.50) | SNCAMAPTPOLBKDM4EALDH1A1 | |
| SCHEMBL1053667 | 0.71 | APP (0.70) | SNCAPOLBNPC1PKMCASP6 | |
| SCHEMBL11460755 | 0.71 | KDM4E (0.63) | RARARARBRARGMAPTPOLB | |
| SCHEMBL15953491 | 0.71 | SREBF2 (0.64) | MAPTKDM4EALDH1A1RECQLL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250270199-A1 | THIAZOLE DERIVATIVES AND METHODS OF USING THE SAME | ARKANSAS STATE UNIV JONESBORO (US) | 2025-08-28 | — | — | US | claimed |
| US-20250270199-A1 | THIAZOLE DERIVATIVES AND METHODS OF USING THE SAME | ARKANSAS STATE UNIV JONESBORO (US) | 2025-08-28 | — | — | US | disclosed |
| WO-2023192595-A1 | THIAZOLE DERIVATIVES AND METHODS OF USING THE SAME | Arkansas State University - Jonesboro (US) | 2023-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250270199-A1 | THIAZOLE DERIVATIVES AND METHODS OF USING THE SAME | TST, GOT2, TPMT | ATP4A 2515/4885ATP4B 3496/4885SNCA 4758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.