SCHEMBL31680258

SCHEMBL31680258

C[C@@H](O)[C@H](N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ IL23R Q5VWK5 15/20 0.58
▸ NPBWR1 P48145 1/20 0.56
▸ NPY2R P49146 3/20 0.55
▸ GHSR Q92847 3/20 0.55
▸ GLP1R P43220 1/20 0.55
▸ GCGR P47871 1/20 0.55
▸ GIPR P48546 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30592733 0.93 GLP1R (0.55) IL23RNPY2RGHSRGLP1RGCGR
SCHEMBL30097937 0.89 IL23R (0.63) IL23RNPY2RGHSR
SCHEMBL31092855 0.89 IL23R (0.67) IL23RNPY2RGHSRGLP1RGCGR
SCHEMBL31146245 0.89 ERAP2 (0.60) IL23RNPBWR1NPY2RGHSRGLP1R
SCHEMBL29883780 0.87 NPBWR1 (0.62) IL23RNPBWR1NPY2RGHSR
SCHEMBL29461984 0.87 NPBWR1 (0.62) IL23RNPBWR1NPY2RGHSR
SCHEMBL29540171 0.87 IL23R (0.64) IL23RNPBWR1GLP1RGCGRGIPR
SCHEMBL31105428 0.86 IL23R (0.71) IL23R
SCHEMBL11331814 0.86 IL23R (0.67) IL23R
SCHEMBL11331799 0.86 IL23R (0.67) IL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250276116-A1 METHODS OF MITIGATING MYOCARDIAL DAMAGE DUE TO EXTRACORPOREAL MEMBRANE OXYGENATION TUFTS MEDICAL CENTER, INC. 2025-09-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250276116-A1 METHODS OF MITIGATING MYOCARDIAL DAMAGE DUE TO EXTRACORPOREAL MEMBRANE OXYGENATION TNNI3, TNNT2, MB IL23R 4785/4885NPBWR1 4341/4885NPY2R 4654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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