Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 2/20 | 0.62 |
| ▸ | NPY2R | P49146 | 3/20 | 0.61 |
| ▸ | GHSR | Q92847 | 2/20 | 0.61 |
| ▸ | NPY4R | P50391 | 4/20 | 0.61 |
| ▸ | NPY1R | P25929 | 3/20 | 0.61 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.61 |
| ▸ | KISS1R | Q969F8 | 10/20 | 0.60 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.59 |
| ▸ | IL1RN | P18510 | 1/20 | 0.58 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29461984 | 0.99 | NPBWR1 (0.62) | NPBWR1NPY2RGHSRNPY4RNPY1R | |
| SCHEMBL29641064 | 0.95 | NPBWR1 (0.66) | NPBWR1NPY2RGHSRNPY4RNPY1R | |
| SCHEMBL29868988 | 0.92 | IL23R (0.60) | NPY2RGHSRNPY4RNPY1RIL23R | |
| SCHEMBL29461988 | 0.92 | IL23R (0.60) | NPY2RGHSRNPY4RNPY1RIL23R | |
| SCHEMBL30092956 | 0.92 | NPBWR1 (0.65) | NPBWR1NPY2RNPY4RNPY1RNPY5R | |
| SCHEMBL29576242 | 0.91 | IL23R (0.59) | NPBWR1NPY2RGHSRNPY4RNPY1R | |
| SCHEMBL30512524 | 0.91 | IL23R (0.67) | NPBWR1NPY2RGHSRIL23R | |
| SCHEMBL30097937 | 0.91 | IL23R (0.63) | NPY2RGHSRIL23R | |
| SCHEMBL29486225 | 0.91 | GHSR (0.57) | NPBWR1NPY2RGHSRKISS1RERAP2 | |
| SCHEMBL30093092 | 0.91 | NPBWR1 (0.65) | NPBWR1NPY2RGHSRNPY4RNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230279051-A1 | METHODS FOR THE TREATMENT OF MITOCHONDRIAL DISEASE | STEALTH BIOTHERAPEUTICS INC. (US) | 2023-09-07 | — | — | US | disclosed |
| US-11672841-B2 | Methods for treating heart disease in a subject with Friedreich's ataxia by an aromatic-cationic peptide | STEALTH BIOTHERAPEUTICS INC. (US) | 2023-06-13 | — | — | US | disclosed |
| US-11420998-B2 | Aromatic-cationic peptides and methods for using same | STEALTH BIOTHERAPEUTICS INC. (US) | 2022-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11672841-B2 | Methods for treating heart disease in a subject with Friedreich's ataxia by an aromatic-cationic peptide | HAGH, OAT, NLN | NPBWR1 1630/4885NPY2R 799/4885GHSR 3852/4885 |
| US-11420998-B2 | Aromatic-cationic peptides and methods for using same | ARG2, ARGLU1, ARG1 | NPBWR1 599/4885NPY2R 730/4885GHSR 4504/4885 |
| US-20230279051-A1 | METHODS FOR THE TREATMENT OF MITOCHONDRIAL DISEASE | NLN, OAT, HAGH | NPBWR1 1973/4885NPY2R 704/4885GHSR 3379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.