SCHEMBL31685263

SCHEMBL31685263

CNC1N(C)C(=O)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2N1C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ATIC P31939 1/20 0.48
▸ ALDH1A1 P00352 2/20 0.48
▸ TP53 P04637 2/20 0.48
▸ HTT P42858 2/20 0.48
▸ BLM P54132 2/20 0.48
▸ GMNN O75496 1/20 0.48
▸ LMNA P02545 1/20 0.48
▸ NFKB1 P19838 1/20 0.48
▸ DNMT1 P26358 1/20 0.48
▸ THPO P40225 1/20 0.48
▸ MTOR P42345 1/20 0.48
▸ RAB9A P51151 1/20 0.48
▸ HBB P68871 1/20 0.48
▸ PMP22 Q01453 1/20 0.48
▸ MAPT P10636 2/20 0.46
▸ CDA P32320 1/20 0.46
▸ KDM4E B2RXH2 2/20 0.45
▸ TDP1 Q9NUW8 1/20 0.45
▸ GAA P10253 1/20 0.45
▸ SMN1; SMN2 Q16637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31685881 0.90 MEN1 (0.47) ATICALDH1A1TP53HTTBLM
SCHEMBL31685751 0.85 ADORA1 (0.47) ATICADORA1
SCHEMBL31685379 0.85 ATIC (0.54) ATICSMN1; SMN2ADORA1
SCHEMBL31685477 0.84 ALDH1A1 (0.53) ATICALDH1A1TP53HTTBLM
SCHEMBL31685850 0.83 ATIC (0.48) ATICALDH1A1TP53HTTBLM
SCHEMBL31685474 0.81 ADRB1 (0.50) TP53HTTLMNADNMT1SMN1; SMN2
SCHEMBL31685395 0.79 ALDH1A1 (0.51) ATICALDH1A1TP53HTTBLM
SCHEMBL1979502 0.76 ATIC (0.53) ATICALDH1A1TP53HTTBLM
SCHEMBL31685472 0.75 LMNA (0.52) ALDH1A1TP53LMNAMAPTTDP1
SCHEMBL31685511 0.74 MEN1 (0.46) ATICALDH1A1TP53HTTBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE TEAM MEDICAL, LLC 2025-09-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE SYNCRIP, SNRPA, RNASE1 ATIC 569/4885ALDH1A1 1153/4885TP53 557/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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