SCHEMBL31685404

SCHEMBL31685404

Nc1ncnc2c1nc(O)n2[C@H]1C[C@H](O)[C@@H](COP(=O)(O)O)O1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.58
▸ TRPM2 O94759 3/20 0.58
▸ ENPP1 P22413 3/20 0.55
▸ P2RY1 P47900 2/20 0.55
▸ SIRT2 Q8IXJ6 1/20 0.54
▸ SIRT1 Q96EB6 1/20 0.54
▸ DNPH1 O43598 1/20 0.51
▸ PRKAB2 O43741 1/20 0.51
▸ LDHA P00338 1/20 0.51
▸ ADRB2 P07550 1/20 0.51
▸ FBP1 P09467 1/20 0.51
▸ SRC P12931 1/20 0.51
▸ ADORA1 P30542 1/20 0.51
▸ P2RY2 P41231 1/20 0.51
▸ PRKAG1 P54619 1/20 0.51
▸ PRKAA2 P54646 1/20 0.51
▸ PDE4D Q08499 1/20 0.51
▸ KCNH2 Q12809 1/20 0.51
▸ PRKAA1 Q13131 1/20 0.51
▸ PDE3A Q14432 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31685468 0.90 POLB (0.49) POLBTRPM2ENPP1P2RY1SIRT2
SCHEMBL16208893 0.89 POLB (0.57) POLBTRPM2ENPP1P2RY1SIRT2
SCHEMBL16208897 0.89 POLB (0.57) POLBTRPM2ENPP1P2RY1SIRT2
SCHEMBL8979282 0.85 TRPM2 (0.61) POLBTRPM2ENPP1P2RY1SIRT2
SCHEMBL24420487 0.83 ADORA3 (0.66) TRPM2PDE4DPDE3ASMN1; SMN2ADORA3
SCHEMBL6302264 0.83 ADORA3 (0.66) TRPM2PDE4DPDE3ASMN1; SMN2ADORA3
SCHEMBL13835070 0.83 ADORA3 (0.66) TRPM2PDE4DPDE3ASMN1; SMN2ADORA3
SCHEMBL30274706 0.83 ADORA3 (0.66) TRPM2PDE4DPDE3ASMN1; SMN2ADORA3
SCHEMBL7882477 0.83 POLB (0.81) POLBTRPM2ENPP1P2RY1DNPH1
SCHEMBL9614573 0.83 SIRT2 (0.75) TRPM2P2RY1SIRT2SIRT1DNPH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE TEAM MEDICAL, LLC 2025-09-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE SYNCRIP, SNRPA, RNASE1 POLB 712/4885TRPM2 3297/4885ENPP1 309/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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