Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM2 | O94759 | 3/20 | 0.61 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.57 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.50 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.50 |
| ▸ | TYMS | P04818 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23215196 | 0.87 | ADORA3 (0.67) | TRPM2ADORA3ADORA2A | |
| SCHEMBL29283549 | 0.87 | ADORA3 (0.67) | TRPM2ADORA3ADORA2A | |
| SCHEMBL29283548 | 0.87 | ADORA3 (0.67) | TRPM2ADORA3ADORA2A | |
| SCHEMBL23240747 | 0.87 | ADORA3 (0.67) | TRPM2ADORA3ADORA2A | |
| SCHEMBL29673048 | 0.87 | ADORA3 (0.67) | TRPM2ADORA3ADORA2A | |
| SCHEMBL19699217 | 0.87 | TRPM2 (0.58) | TRPM2SIRT2SIRT1POLBADORA3 | |
| SCHEMBL31685404 | 0.85 | POLB (0.58) | TRPM2SIRT2SIRT1POLBADORA3 | |
| SCHEMBL16208897 | 0.84 | POLB (0.57) | TRPM2SIRT2SIRT1POLBENPP1 | |
| SCHEMBL16208893 | 0.84 | POLB (0.57) | TRPM2SIRT2SIRT1POLBENPP1 | |
| SCHEMBL27064221 | 0.80 | ADORA2A (0.53) | TRPM2ADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512486-A | Single step signal group-imidazole labeling of organic phosphate groups under aqueous conditions | NORTHEASTERN UNIVERSITY (US) | 1996-04-30 | — | — | US | disclosed |