SCHEMBL316895

SCHEMBL316895

C=Cc1ccc(CCC(=C)C(=O)O)cc1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 5/20 0.41
ALDH1A1 P00352 3/20 0.41
KEAP1 Q14145 1/20 0.39
BCHE P06276 2/20 0.38
ACHE P22303 2/20 0.38
TDP1 Q9NUW8 1/20 0.37
HDAC1 Q13547 1/20 0.37
PSMD14 O00487 1/20 0.37
LMNA P02545 1/20 0.37
TSHR P16473 1/20 0.37
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
THRB P10828 1/20 0.36
FFAR4 Q5NUL3 1/20 0.36
HDAC2 Q92769 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3627111 0.85 FFAR1 (0.59) FFAR1KEAP1LMNACA1CA2
Styrene SCHEMBL14801675 0.84 ALDH1A1 (0.50) FFAR1ALDH1A1KEAP1TDP1HDAC1
Hydrochloric Acid SCHEMBL3623874 0.83 FFAR1 (0.57) FFAR1KEAP1LMNACA1CA2
SCHEMBL3816810 0.83 ALDH1A1 (0.42) ALDH1A1TDP1PSMD14LMNATSHR
SCHEMBL9679627 0.82 BCHE (0.53) FFAR1ALDH1A1KEAP1BCHEACHE
SCHEMBL3371585 0.82 FAAH (0.41) FFAR1ALDH1A1KEAP1TDP1TSHR
SCHEMBL1137129 0.81 ESR1 (0.50) FFAR1ALDH1A1TDP1LMNATSHR
SCHEMBL7634724 0.81 FFAR1 (0.44) FFAR1ALDH1A1KEAP1TDP1HDAC1
SCHEMBL17940817 0.81 FFAR1 (0.64) FFAR1ALDH1A1KEAP1TDP1HDAC1
SCHEMBL30529 0.80 KEAP1 (0.61) FFAR1ALDH1A1KEAP1TDP1HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9238715-B2 Polymerizable composition for ophthalmic and medical use and antimicrobial composition obtained by polymerizing the polymerizable composition NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2016-01-19 US claimed
EP-1696257-B1 CONTACT LENS MATERIAL MENICON CO LTD (JP) 2012-11-21 EP claimed
EP-0722110-B1 Water absorptive soft contact lens MENICON CO LTD (JP) 2003-09-17 EP claimed
EP-0944656-B1 PROCESS FOR PREPARING RUBBER-MODIFIED MOULDING COMPOUNDS BASF AG (DE) 2001-07-11 EP claimed
EP-0600269-B1 Soft ocular lens material MENICON CO LTD (JP) 1998-02-04 EP claimed
US-11688845-B2 Method for passive metal activation and uses thereof TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2023-06-27 US disclosed
EP-3642284-B1 CURABLE ORGANOPOLYSILOXANE COMPOSITIONS WACKER CHEMIE AG (DE) 2022-06-01 EP disclosed
EP-3710414-B1 CURABLE ORGANOPOLYSILOXANE COMPOSITIONS WACKER CHEMIE AG (DE) 2021-04-07 EP disclosed
EP-3127183-B1 METHOD FOR PASSIVE METAL ACTIVATION AND USES THEREOF TECHNION RES & DEV FOUNDATION (IL) 2020-09-30 EP disclosed
EP-3710414-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITIONS Wacker Chemie AG (DE) 2020-09-23 EP disclosed
US-20200235374-A1 METHOD FOR PASSIVE METAL ACTIVATION AND USES THEREOF TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2020-07-23 US disclosed
EP-3121643-B1 OPHTHALMIC LENS MENICON CO LTD (JP) 2020-07-22 EP disclosed
EP-1030194-B1 Material for a soft intraocular lens MENICON CO LTD (JP) 2002-12-04 EP disclosed
EP-0944654-B1 ANIONIC POLYMERISATION OF ACRYLATES AND METHACRYLATES BASF AG (DE) 2002-03-20 EP disclosed
US-6277940-B1 TRANSPARENCY AND FLEXIBILITY, REFRACTIVE INDEX, CAN BE INSERTED FROM A SMALL INCISION MENICON CO. LTD (JP) 2001-08-21 US disclosed
EP-0944656-B1 PROCESS FOR PREPARING RUBBER-MODIFIED MOULDING COMPOUNDS BASF AG (DE) 2001-07-11 EP disclosed
EP-1030194-A1 Material for a soft intraocular lens Menicon Co., Ltd. (JP) 2000-08-23 EP disclosed
US-6015874-A CURING AGENT FOR HYDROPHILIC, TRANSPARENT, DURABLE POLYMERIC CONTACT OR INTRAOCULAR LENSES WHICH ALSO ABSORB ULTRA VIOLET RADIATION AND ARE OXYGEN PERMEABLE MENICON CO., LTD. (JP) 2000-01-18 US disclosed
EP-0913713-A2 Crosslinkable compound and an optical material employing it Menicon Co., Ltd. (JP) 1999-05-06 EP disclosed
US-5519070-A FLUORINE, ALKOXY POLYSILOXANE COPOLYMERS FOR INTRAOCULAR LENSES MENICON CO., LTD. (JP) 1996-05-21 US disclosed