Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31691466 | 0.85 | LMNA (0.45) | MRGPRX4KDM4EALDH1A1MAPTLMNA | |
| SCHEMBL9089861 | 0.77 | MAPK1 (0.44) | KDM4EHSD17B10ALDH1A1MAPTLMNA | |
| SCHEMBL31691426 | 0.76 | ALOX15 (0.47) | KDM4EHSD17B10ALDH1A1ALOX15MAPT | |
| SCHEMBL19474955 | 0.76 | ALDH1A1 (0.56) | KDM4EHSD17B10ALDH1A1ALOX15LMNA | |
| SCHEMBL16682715 | 0.74 | MAPT (0.43) | MRGPRX4KDM4EHSD17B10ALDH1A1MAPT | |
| SCHEMBL31691389 | 0.73 | KMT2A (0.47) | KDM4EALDH1A1ALOX15MAPTHPGD | |
| SCHEMBL23422973 | 0.71 | MAPT (0.40) | MRGPRX4KDM4EHSD17B10ALDH1A1MAPT | |
| SCHEMBL7834117 | 0.71 | PKM (0.60) | KDM4EHSD17B10ALDH1A1ALOX15MAPT | |
| SCHEMBL31172637 | 0.70 | KLKB1 (0.46) | KDM4EHSD17B10ALDH1A1ALOX15MAPT | |
| SCHEMBL29576494 | 0.69 | KDM4E (0.68) | KDM4EALDH1A1MAPTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250304535-A1 | KAT6 Inhibitors | BEIGENE SWITZERLAND GMBH (CH) | 2025-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250304535-A1 | KAT6 Inhibitors | KAT6A, KAT6B, KAT2A | MRGPRX4 3707/4885KDM4E 349/4885HSD17B10 1155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.