Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 1/20 | 0.49 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.48 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | NEK2 | P51955 | 1/20 | 0.44 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2880574 | 0.98 | PTPN22 (0.50) | CTRB1PTPN22LDHAERN1THRB | |
| SCHEMBL8445295 | 0.96 | CTRB1 (0.49) | CTRB1PTPN22LDHAERN1THRB | |
| Potassium Ion SCHEMBL31385186 | 0.96 | CTRB1 (0.49) | CTRB1PTPN22LDHAERN1THRB | |
| SCHEMBL339569 | 0.96 | CTRB1 (0.49) | CTRB1PTPN22LDHAERN1THRB | |
| Potassium Ion SCHEMBL1819744 | 0.96 | CTRB1 (0.49) | CTRB1PTPN22LDHAERN1THRB | |
| Hydrochloric Acid SCHEMBL27766336 | 0.81 | CTRB1 (0.64) | CTRB1PTPN22LDHAERN1CHEK1 | |
| SCHEMBL88069 | 0.81 | CTRB1 (0.64) | CTRB1PTPN22LDHAERN1CHEK1 | |
| SCHEMBL30383446 | 0.81 | CTRB1 (0.64) | CTRB1PTPN22LDHAERN1CHEK1 | |
| Potassium SCHEMBL2292044 | 0.79 | CTRB1 (0.62) | CTRB1PTPN22LDHAERN1CHEK1 | |
| SCHEMBL5145547 | 0.79 | CA1 (0.60) | CTRB1PTPN22LDHAERN1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59227300-A | — | — | None | — | — | JP | disclosed |
| EP-1661931-B1 | CONDUCTIVE POLYMER AND SOLID ELECTROLYTIC CAPACITOR USING SAME | TAYCA CORP (JP) | 2015-11-18 | — | — | EP | disclosed |
| US-7651639-B2 | Conductive polymer and solid electrolytic capacitor using the same | TAYCA CORPORATION (JP) | 2010-01-26 | — | — | US | disclosed |
| US-20080135810-A1 | Conductive polymer and solid electrolytic capacitor using the same | TAYCA CORPORATION (JP) | 2008-06-12 | — | — | US | disclosed |
| US-20060223976-A1 | Conductive polymer and solid electrolytic capacitor using same | TAYCA CORPORATION (JP) | 2006-10-05 | — | — | US | disclosed |
| EP-1661931-A1 | CONDUCTIVE POLYMER AND SOLID ELECTROLYTIC CAPACITOR USING SAME | Tayca Corporation (JP) | 2006-05-31 | — | — | EP | disclosed |
| JP-S59227300-A | CONDENSATION REACTION | AMANO PHARMACEUT CO LTD | 1984-12-20 | — | — | JP | disclosed |