Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.49 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.48 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | NEK2 | P51955 | 1/20 | 0.44 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.44 |
| ▸ | PKLR | P30613 | 2/20 | 0.41 |
| ▸ | DUSP5 | Q16690 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2880574 | 0.98 | PTPN22 (0.50) | CTRB1THRBPTPN22LDHAERN1 | |
| SCHEMBL8445295 | 0.96 | CTRB1 (0.49) | CTRB1THRBPTPN22LDHAERN1 | |
| SCHEMBL3169181 | 0.96 | CTRB1 (0.49) | CTRB1THRBPTPN22LDHAERN1 | |
| Potassium Ion SCHEMBL31385186 | 0.96 | CTRB1 (0.49) | CTRB1THRBPTPN22LDHAERN1 | |
| Potassium Ion SCHEMBL1819744 | 0.96 | CTRB1 (0.49) | CTRB1THRBPTPN22LDHAERN1 | |
| SCHEMBL88069 | 0.81 | CTRB1 (0.64) | CTRB1PTPN22LDHAERN1CHEK1 | |
| Hydrochloric Acid SCHEMBL27766336 | 0.81 | CTRB1 (0.64) | CTRB1PTPN22LDHAERN1CHEK1 | |
| SCHEMBL30383446 | 0.81 | CTRB1 (0.64) | CTRB1PTPN22LDHAERN1CHEK1 | |
| SCHEMBL29576653 | 0.80 | DUSP5 (0.46) | THRBPKLRDUSP5PTPN1PGAM1 | |
| SCHEMBL3233249 | 0.79 | CA1 (0.41) | CTRB1THRBERN1DUSP5NR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119162856-A | Environment-friendly low-phenol color fixing agent and preparation method thereof | 广东宏昊化工有限公司 | 2024-12-20 | — | — | CN | claimed |
| CN-115976519-B | Chromium etching solution for stripping development and application thereof | 武汉梵佳鑫科技有限公司 | 2024-08-30 | — | — | CN | claimed |
| CN-118390316-A | Nylon dyeing and fixing one-bath color fastness improver, preparation method and nylon fabric dyeing method | 东莞市中纺化工有限公司 | 2024-07-26 | — | — | CN | claimed |
| CN-118390317-A | Printing and dyeing processing method for improving wet treatment color fastness of nylon spandex elastic knitted fabric | 东莞市中纺化工有限公司 | 2024-07-26 | — | — | CN | claimed |
| CN-115960682-B | Low-VOC (volatile organic compound) photosensitive resin developing cleaning agent for 3D printing and preparation method thereof | 深圳市科玺化工有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-115976519-A | Chromium etching solution for deplating development and application thereof | 武汉梵佳鑫科技有限公司 | 2023-04-18 | — | — | CN | claimed |
| CN-115960682-A | Low-VOC photosensitive resin developing cleaning agent for 3D printing and preparation method thereof | 深圳市科玺化工有限公司 | 2023-04-14 | — | — | CN | claimed |
| WO-2023003410-A1 | COMPOSITION FOR AUTOIMMUNE BUILDER OF PLANTS AND USAGE METHOD USING SAME | 농업회사법인 주식회사 아그로비즈 | 2023-01-26 | — | — | WO | claimed |
| CN-113621375-B | Quartz wafer etching additive and preparation method thereof | 深圳市科玺化工有限公司 | 2022-07-01 | — | — | CN | claimed |
| CN-114214677-A | Acidic copper plating deep hole agent, preparation method thereof and electroplating method | 佛山亚特表面技术材料有限公司 | 2022-03-22 | — | — | CN | claimed |
| CN-113621375-A | Quartz wafer etching additive and preparation method thereof | 深圳市科玺化工有限公司 | 2021-11-09 | — | — | CN | claimed |
| CN-109323996-B | Fungus detection kit | 宁波市奉化区人民医院 | 2021-09-07 | — | — | CN | claimed |
| CN-109323996-A | A kind of fungal detection kit | 宁波市奉化区人民医院 | 2019-02-12 | — | — | CN | claimed |
| CN-103757669-B | Electroplate tin liquor | Guangdong Guanghua Science and Technology Co., Ltd. (CN) | 2016-05-25 | — | — | CN | claimed |
| CN-102305787-A | Preparation of fungal (1-3)-beta-D-Glucan colorimetric assay kit and using method for colorimetric assay kit | TIANJIN YIRUI BIO ENGINEERING CO LTD | 2012-01-04 | — | — | CN | claimed |
| CN-102305788-A | Preparation of gram-negative bacterial lipopolysaccharide (endotoxin) colorimetric assay kit and using method for colorimetric assay kit | TIANJIN YIRUI BIO ENGINEERING CO LTD | 2012-01-04 | — | — | CN | claimed |
| US-6582657-B2 | Useful for detection and quantification of a dosage of ionizing radiation | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-06-24 | — | — | US | claimed |
| WO-2002046728-A1 | DOSIMETER AND METHOD FOR USING THE SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2002-06-13 | — | — | WO | claimed |
| US-20020068016-A1 | Dosimeter and method for using the same | LOS ALAMOS NATIONAL SECURITY, LLC | 2002-06-06 | — | — | US | claimed |
| US-4042335-A | Integral element for analysis of liquids | EASTMAN KODAK COMPANY (US) | 1977-08-16 | — | — | US | claimed |