Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 3/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | PHGDH | O43175 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31694678 | 0.78 | TDP1 (0.61) | GAAKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL4004877 | 0.75 | DRD4 (0.76) | GAAKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL31694688 | 0.72 | ADAMTS5 (0.50) | GAAKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL30964310 | 0.71 | TRPV1 (0.51) | GAAMAPTALDH1A1L3MBTL1DRD4 | |
| SCHEMBL30964267 | 0.70 | TSHR (0.57) | GAAKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL28972664 | 0.70 | ADAMTS5 (0.61) | KMT2AMEN1MAPTLMNADRD4 | |
| SCHEMBL30964285 | 0.68 | TRPV1 (0.52) | KMT2AMEN1MAPTALDH1A1DRD4 | |
| SCHEMBL30964256 | 0.67 | HTR1A (0.56) | GAAKMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL3799761 | 0.67 | KMT2A (0.67) | KMT2AMEN1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL4005427 | 0.67 | DRD4 (0.78) | MAPTALDH1A1LMNADRD4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4628098-A1 | TPK AGONIST AND METHOD FOR USING SAME TO TREAT NEURODEGENERATIVE DISEASES | Shanghai Raising Pharmaceutical Co., Ltd. (CN) | 2025-10-08 | — | — | EP | disclosed |