Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 8/20 | 0.55 |
| ▸ | DRD4 | P21917 | 5/20 | 0.55 |
| ▸ | DRD3 | P35462 | 2/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PHGDH | O43175 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30964256 | 0.88 | HTR1A (0.56) | MAPTMAPK1DRD2DRD3HTR2A | |
| SCHEMBL30964310 | 0.86 | TRPV1 (0.51) | ALDH1A1MAPTMAPK1DRD2DRD4 | |
| SCHEMBL30964285 | 0.83 | TRPV1 (0.52) | ALDH1A1MAPTDRD2DRD4DRD3 | |
| SCHEMBL29961296 | 0.75 | DRD2 (0.64) | ALDH1A1MAPTDRD2DRD4DRD3 | |
| SCHEMBL27979642 | 0.73 | HTT (0.89) | TSHRALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL3407378 | 0.72 | DRD2 (0.71) | DRD2DRD4DRD3HTR2A | |
| SCHEMBL3407385 | 0.72 | DRD2 (0.71) | DRD2DRD4DRD3HTR2A | |
| SCHEMBL30964278 | 0.72 | CXCR3 (0.55) | TSHRALDH1A1MAPK1DRD2DRD3 | |
| SCHEMBL13234916 | 0.70 | MAPT (0.70) | ALDH1A1MAPTLMNAHTR2AGAA | |
| SCHEMBL31694679 | 0.70 | GAA (0.60) | ALDH1A1MAPTLMNADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118121699-A | TPK agonists and methods of using the same for treating neurodegenerative diseases | 上海日馨医药科技股份有限公司 | 2024-06-04 | — | — | CN | disclosed |