Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.56 |
| ▸ | HTR2A | P28223 | 3/20 | 0.56 |
| ▸ | HTR1D | P28221 | 3/20 | 0.56 |
| ▸ | HTR1B | P28222 | 3/20 | 0.56 |
| ▸ | HTR2C | P28335 | 2/20 | 0.56 |
| ▸ | HTR7 | P34969 | 2/20 | 0.56 |
| ▸ | HTR6 | P50406 | 2/20 | 0.56 |
| ▸ | RBP4 | P02753 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30964267 | 0.88 | TSHR (0.57) | HTR2AGAAMAPTRAB9ADRD3 | |
| SCHEMBL30964285 | 0.84 | TRPV1 (0.52) | HTR2AMAPTTRPV1RAB9ADRD3 | |
| SCHEMBL30964310 | 0.83 | TRPV1 (0.51) | HTR2AGAAMAPTTRPV1L3MBTL1 | |
| SCHEMBL30964278 | 0.81 | CXCR3 (0.55) | HTR1AHTR2ARBP4GAADRD3 | |
| SCHEMBL6716446 | 0.78 | HTR1A (0.55) | HTR1AHTR2AHTR1DHTR1BHTR2C | |
| SCHEMBL30964244 | 0.76 | ALDH1A1 (0.61) | GAAMAPTL3MBTL1MEN1HTT | |
| SCHEMBL30964277 | 0.75 | ALDH1A1 (0.59) | GAAMAPTL3MBTL1MEN1HTT | |
| SCHEMBL30964288 | 0.74 | KMT2A (0.58) | HTR1AHTR2AGAAMAPTDRD3 | |
| SCHEMBL6717734 | 0.74 | HTR1A (0.56) | HTR1AHTR2AHTR1DHTR1BHTR2C | |
| SCHEMBL30964242 | 0.74 | DRD2 (0.62) | HTR1AHTR2ADRD3DRD2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118121699-A | TPK agonists and methods of using the same for treating neurodegenerative diseases | 上海日馨医药科技股份有限公司 | 2024-06-04 | — | — | CN | disclosed |