Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.51 |
| ▸ | DRD2 | P14416 | 10/20 | 0.49 |
| ▸ | DRD3 | P35462 | 8/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 3/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GOT1 | P17174 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30964285 | 0.89 | TRPV1 (0.52) | TRPV1DRD2DRD3NPC1ALDH1A1 | |
| SCHEMBL30964267 | 0.86 | TSHR (0.57) | DRD2DRD3NPC1ALDH1A1RAB9A | |
| SCHEMBL30964256 | 0.83 | HTR1A (0.56) | TRPV1DRD2DRD3NPC1RAB9A | |
| SCHEMBL30964289 | 0.72 | DRD2 (0.55) | DRD2DRD3 | |
| SCHEMBL31694679 | 0.71 | GAA (0.60) | DRD2DRD3ALDH1A1RAB9ADRD4 | |
| SCHEMBL27237946 | 0.69 | DRD2 (0.60) | TRPV1DRD2DRD3HTR2ADRD4 | |
| SCHEMBL3714314 | 0.68 | TRPV1 (0.60) | TRPV1NPC1ALDH1A1RAB9ANPSR1 | |
| SCHEMBL30965800 | 0.67 | DRD2 (0.58) | TRPV1DRD2DRD3HTR2ADRD4 | |
| SCHEMBL6907029 | 0.67 | ALDH1A1 (0.67) | NPC1ALDH1A1RAB9ANPSR1MAPT | |
| SCHEMBL28972664 | 0.67 | ADAMTS5 (0.61) | DRD2DRD3HTR2ADRD4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118121699-A | TPK agonists and methods of using the same for treating neurodegenerative diseases | 上海日馨医药科技股份有限公司 | 2024-06-04 | — | — | CN | disclosed |