Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.59 |
| ▸ | TDP2 | O95551 | 2/20 | 0.47 |
| ▸ | TYMS | P04818 | 3/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10138376 | 1.00 | PBRM1 (0.59) | PBRM1TDP2TYMSCASP1CASP7 | |
| SCHEMBL12500758 | 0.88 | MAOA (0.48) | PBRM1TDP2TYMSHSD17B1CES1 | |
| SCHEMBL3665755 | 0.88 | MAOA (0.53) | PBRM1TDP2TYMSHSD17B1CES1 | |
| SCHEMBL6370185 | 0.84 | TDP2 (0.48) | PBRM1TDP2TYMSCES1TGM2 | |
| SCHEMBL16082766 | 0.83 | CASP1 (0.59) | PBRM1TDP2CASP1CASP7HSD17B10 | |
| SCHEMBL8501316 | 0.80 | TDP2 (0.58) | PBRM1TDP2TYMSCES1TGM2 | |
| SCHEMBL5546838 | 0.76 | PBRM1 (0.61) | PBRM1TYMSCASP1CASP7HSD17B10 | |
| SCHEMBL1151032 | 0.74 | PBRM1 (0.59) | PBRM1TYMSCASP1CASP7HSD17B10 | |
| SCHEMBL7891254 | 0.74 | PBRM1 (0.59) | PBRM1TYMSCASP1CASP7HSD17B10 | |
| SCHEMBL8871212 | 0.74 | PBRM1 (0.59) | PBRM1TYMSCASP1CASP7HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250313574-A1 | SIALIC ACID DERIVATIVES AND METHODS OF USING SAME | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2025-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250313574-A1 | SIALIC ACID DERIVATIVES AND METHODS OF USING SAME | NEU1, NEU2, NEU4 | PBRM1 4863/4885TDP2 2424/4885TYMS 1409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.