⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL11764328 | 0.94 | CYP2A6 (0.48) | — | |
| SCHEMBL6050741 | 0.82 | CES2 (0.67) | — | |
| (E)-1,2-Di-P-Tolylethene SCHEMBL6480905 | 0.73 | CYP2A6 (0.58) | — | |
| SCHEMBL318785 | 0.73 | NFE2L2 (0.74) | — | |
| SCHEMBL318786 | 0.73 | NFE2L2 (0.74) | — | |
| (E)-1,2-Di-P-Tolylethene SCHEMBL1793692 | 0.73 | NFE2L2 (0.74) | — | |
| (E)-1,2-Di-P-Tolylethene SCHEMBL1305580 | 0.73 | NFE2L2 (0.74) | — | |
| SCHEMBL1149391 | 0.73 | CYP2A6 (0.58) | — | |
| (E)-1,2-Di-P-Tolylethene SCHEMBL1305582 | 0.73 | NFE2L2 (0.74) | — | |
| SCHEMBL11662727 | 0.73 | NFE2L2 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 967 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120117949-A | Method for directly preparing tertiary amine compound from aromatic aldehyde, ketone and secondary amine | 湖南大学 | 2025-06-10 | — | — | CN | claimed |
| CN-120058569-A | Preparation method of p-methylsulfonyl benzaldehyde | 湖北武荆化工新材料有限公司 | 2025-05-30 | — | — | CN | claimed |
| CN-119219504-B | Method for synthesizing triarylmethane molecular skeleton by aromatic aldehyde and hydrazine hydrochloride substance | 山东金科力电源科技有限公司 | 2025-03-14 | — | — | CN | claimed |
| CN-119462444-A | Synthesis method of p-methylthiobenzaldehyde | 江苏八巨药业有限公司 | 2025-02-18 | — | — | CN | claimed |
| CN-119219504-A | Method for synthesizing triarylmethane molecular skeleton by aromatic aldehyde and hydrazine hydrochloride substance | 山东金科力电源科技有限公司 | 2024-12-31 | — | — | CN | claimed |
| CN-119101058-A | Porphyrin compound for biological imaging and sonodynamic therapy and preparation method and application thereof | 徐州医科大学 | 2024-12-10 | — | — | CN | claimed |
| CN-118852032-A | Alpha, beta-unsaturated ketone derivative, preparation method and application thereof | 赣南医科大学 | 2024-10-29 | — | — | CN | claimed |
| CN-118853779-A | Preparation method and application of sulindac and intermediate thereof | 江苏暨明医药科技有限公司 | 2024-10-29 | — | — | CN | claimed |
| CN-118745145-A | 2-Hydroxypyridine derivatives, and synthetic method and application thereof | 湖南大学 | 2024-10-08 | — | — | CN | claimed |
| CN-118164878-B | Preparation method of p-methylsulfonyl benzaldehyde | 山东德澳精细化学品有限公司 | 2024-07-26 | — | — | CN | claimed |
| US-4916128-A | Thiadiazinones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-04-10 | — | — | US | claimed |
| EP-0206241-B1 | PROCESS FOR THE PREPARATION OF CIS-5-FLUORO-2-METHYL-1-(4-METHYLTHIOBENZYLIDENE)-INDENE-3-ACETIC ACID | ZAMBON S.p.A. (IT) | 1989-04-19 | — | — | EP | claimed |
| US-4748271-A | Process for the preparation of cis-5-fluoro-2-methyl-1-(4-methyl-thiobenzylidene)-indene-3-acetic acid | ZAMBON S.P.A. (IT) | 1988-05-31 | — | — | US | claimed |
| EP-0206241-A1 | Process for the preparation of cis-5-fluoro-2-methyl-1-(4-methylthiobenzylidene)-indene-3-acetic acid | ZAMBON S.p.A. (IT) | 1986-12-30 | — | — | EP | claimed |
| US-4614833-A | 2-halo-pyridines | LACER, S.A. (ES) | 1986-09-30 | — | — | US | claimed |
| US-4582903-A | Synthesis of unsaturated hydantoins with an inexpensive catalyst | STAUFFER CHEMICAL COMPANY (US) | 1986-04-15 | — | — | US | claimed |
| EP-0071791-B1 | TRICHLOROMETHYLTHIOBENZYL HALIDES AND PROCESS FOR PREPARARING META OR PARA TRICHLOROMETHYLTHIOBENZYL HALIDES | BASF Aktiengesellschaft (DE) | 1985-05-08 | — | — | EP | claimed |
| US-4345072-A | Process for the production of 5-arylidene hydantoins (B) | DEGUSSA AG (DE) | 1982-08-17 | — | — | US | claimed |
| US-4043942-A | Modified nickel catalyst systems and their use in reductive alkylation reactions | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1977-08-23 | — | — | US | claimed |
| US-3998875-A | PROCESS OF PREPARING 5-FLUORO-2-METHYL-1-(PARAMETHYLSULFINYLBENZYLIDENE)-INDENYL-3-ACETIC ACID | MERCK & CO., INC. (US) | 1976-12-21 | — | — | US | claimed |