Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31697911 | 0.91 | GPR119 (0.43) | GPR119CRBNDDB1CHEK2 | |
| SCHEMBL27121298 | 0.91 | GPR119 (0.43) | GPR119CRBNDDB1CHEK2 | |
| SCHEMBL29281606 | 0.90 | DDB1 (0.38) | CRBNDDB1KDM4EKMT2A | |
| SCHEMBL27123951 | 0.90 | GPR119 (0.40) | GPR119CRBNCHEK2 | |
| SCHEMBL31024405 | 0.90 | GPR119 (0.40) | GPR119CRBNCHEK2 | |
| SCHEMBL31697865 | 0.89 | RBP4 (0.39) | CRBNDDB1KMT2A | |
| SCHEMBL31024363 | 0.89 | GPR119 (0.39) | GPR119CRBNDDB1CHEK2 | |
| SCHEMBL27137196 | 0.89 | GPR119 (0.39) | GPR119CRBNDDB1CHEK2 | |
| SCHEMBL31024364 | 0.86 | MEN1 (0.42) | GPR119CRBNDDB1CHEK2ABL1 | |
| SCHEMBL27124609 | 0.86 | MEN1 (0.42) | GPR119CRBNDDB1CHEK2ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4631942-A1 | PAN-KRAS DEGRADING AGENT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Leadingtac Pharmaceutical (Shaoxing) Co., Ltd. (CN) | 2025-10-15 | — | — | EP | disclosed |