Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.38 |
| ▸ | FASN | P49327 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29281606 | 0.92 | DDB1 (0.38) | GFERDDB1CRBNALDH1A1TP53 | |
| SCHEMBL27137025 | 0.90 | RBP4 (0.38) | RBP4CRBNALDH1A1HPGDKMT2A | |
| SCHEMBL27123888 | 0.90 | MGLL (0.39) | RBP4MGLLHSD11B1 | |
| SCHEMBL31697885 | 0.90 | MGLL (0.39) | RBP4MGLLHSD11B1 | |
| SCHEMBL31697794 | 0.89 | GPR119 (0.41) | DDB1CRBNKMT2A | |
| SCHEMBL30015004 | 0.88 | RBP4 (0.38) | RBP4HTR7MGLLHSD11B1 | |
| SCHEMBL27137731 | 0.88 | RBP4 (0.38) | RBP4HTR7MGLLHSD11B1 | |
| SCHEMBL30014591 | 0.88 | MGLL (0.38) | RBP4MGLLHSD11B1 | |
| SCHEMBL27148092 | 0.88 | MGLL (0.38) | RBP4MGLLHSD11B1 | |
| SCHEMBL27124624 | 0.83 | MGLL (0.41) | RBP4MGLLHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4631942-A1 | PAN-KRAS DEGRADING AGENT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Leadingtac Pharmaceutical (Shaoxing) Co., Ltd. (CN) | 2025-10-15 | — | — | EP | disclosed |