Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.43 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27121298 | 1.00 | GPR119 (0.43) | GPR119PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27137196 | 0.92 | GPR119 (0.39) | GPR119CRBNDDB1CHEK2 | |
| SCHEMBL31024363 | 0.92 | GPR119 (0.39) | GPR119CRBNDDB1CHEK2 | |
| SCHEMBL31697794 | 0.91 | GPR119 (0.41) | GPR119CRBNDDB1CHEK2 | |
| SCHEMBL28891876 | 0.90 | NR3C1 (0.38) | CRBNBACE1ALDH1A1 | |
| SCHEMBL30278930 | 0.90 | PDE4A (0.45) | GPR119PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27137025 | 0.90 | RBP4 (0.38) | CRBNALDH1A1POLBCYP2C19 | |
| SCHEMBL27123951 | 0.88 | GPR119 (0.40) | GPR119CRBNCHEK2 | |
| SCHEMBL31024405 | 0.88 | GPR119 (0.40) | GPR119CRBNCHEK2 | |
| SCHEMBL25583436 | 0.87 | SOS1 (0.44) | GPR119PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4631942-A1 | PAN-KRAS DEGRADING AGENT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Leadingtac Pharmaceutical (Shaoxing) Co., Ltd. (CN) | 2025-10-15 | — | — | EP | disclosed |