Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 4/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31697865 | 0.92 | RBP4 (0.39) | DDB1CRBNALDH1A1TP53HPGD | |
| SCHEMBL31697794 | 0.90 | GPR119 (0.41) | DDB1CRBNKDM4EKMT2A | |
| SCHEMBL28891876 | 0.90 | NR3C1 (0.38) | CRBNALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL29201746 | 0.90 | MGLL (0.39) | MGLL | |
| SCHEMBL27137184 | 0.88 | HSD11B1 (0.35) | HTR7MGLL | |
| SCHEMBL27141895 | 0.87 | MGLL (0.38) | MGLL | |
| SCHEMBL30014759 | 0.87 | MGLL (0.38) | MGLL | |
| SCHEMBL28783557 | 0.84 | DDB1 (0.44) | DDB1CRBNALDH1A1TP53HPGD | |
| SCHEMBL27143092 | 0.83 | MGLL (0.42) | MGLL | |
| SCHEMBL27137025 | 0.82 | RBP4 (0.38) | CRBNALDH1A1HPGDSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917410-A | Pan-KRAS degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2024-04-23 | — | — | CN | disclosed |