Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2498853 | 0.83 | ALDH1A1 (0.53) | LMNAALDH1A1MAPTHCAR3MEN1 | |
| SCHEMBL13554669 | 0.81 | LMNA (0.50) | LMNAALDH1A1MAPTHCAR3MEN1 | |
| SCHEMBL17243849 | 0.81 | LMNA (0.50) | LMNAALDH1A1MAPTHCAR3MEN1 | |
| SCHEMBL3041310 | 0.81 | RAB9A (0.51) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL2021092 | 0.80 | TDP1 (0.44) | LMNAALDH1A1MAPTHCAR3MEN1 | |
| SCHEMBL23273490 | 0.80 | MEN1 (0.52) | LMNAALDH1A1MAPTHCAR3MEN1 | |
| SCHEMBL31180668 | 0.79 | LMNA (0.43) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL31440090 | 0.78 | GPR35 (0.43) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2314495 | 0.77 | MAPT (0.48) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL762770 | 0.76 | MAPT (0.68) | LMNAALDH1A1MAPTHCAR3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260014147-A1 | STAT6 DEGRADERS | GILEAD SCIENCES INC (US) | 2026-01-15 | — | — | US | disclosed |
| US-20250325677-A1 | STAT6 DEGRADERS | GILEAD SCIENCES INC (US) | 2025-10-23 | — | — | US | disclosed |
| US-20250320206-A1 | STAT6 DEGRADERS | GILEAD SCIENCES INC (US) | 2025-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250325677-A1 | STAT6 DEGRADERS | STAT6, STAT5B, STAT1 | LMNA 2978/4885ALDH1A1 959/4885MAPT 1017/4885 |
| US-20260014147-A1 | STAT6 DEGRADERS | STAT6, NCOR1, CBR1 | LMNA 1900/4885ALDH1A1 1790/4885MAPT 4225/4885 |
| US-20250320206-A1 | STAT6 DEGRADERS | STAT6, STAT5B, STAT1 | LMNA 2978/4885ALDH1A1 959/4885MAPT 1017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.