Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | MPI | P34949 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3170137 | 1.00 | KDM4E (0.57) | KDM4EKMT2AMEN1EGFRPTGS2 | |
| SCHEMBL212207 | 0.89 | KDM4E (0.71) | KDM4EKMT2AMEN1PTGS2LMNA | |
| SCHEMBL7296406 | 0.83 | MAPT (0.53) | KDM4EKMT2AMEN1PTGS2MAPT | |
| SCHEMBL7296409 | 0.83 | MAPT (0.53) | KDM4EKMT2AMEN1PTGS2MAPT | |
| SCHEMBL31565026 | 0.83 | LMNA (0.46) | KDM4EKMT2AMEN1LMNAMAPT | |
| SCHEMBL92088 | 0.83 | LMNA (0.46) | KDM4EKMT2AMEN1LMNAMAPT | |
| SCHEMBL14395714 | 0.83 | PTGS2 (0.44) | KDM4EKMT2AMEN1EGFRPTGS2 | |
| SCHEMBL11000571 | 0.83 | KDM4E (0.53) | KDM4EKMT2AMEN1EGFRPTGS2 | |
| SCHEMBL27641132 | 0.82 | KDM4E (0.51) | KDM4EKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL10924757 | 0.80 | KDM4E (0.56) | KDM4EKMT2AMEN1EGFRPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095035-B1 | METHOD FOR PREPARING 4-(3-PYRIDINYL)-1H-IMIDAZOLE AND THE INTERMEDIATES USED | AVENTIS PHARMA SA (FR) | 2010-03-17 | — | — | EP | claimed |
| US-6353108-B1 | 1-(3-PYRIDINYL)-ETHANONE O-((4-METHYLPHENYL) SULPHONYL) OXIME FORMS 3-(2H-AZIRIN-3-YL)-PYRIDINE WHICH IS REACTED WITH ACID AND ALCOHOL TO OBTAIN THE 2,2-DIMETHOXY-2-(3-PYRIDINYL) ETHYL-AMINE WHICH IS REACTED WITH AN AMIDE AND CYCLIZED; INTERMEDIATES ARE NOT ISOLATED | AVENTIS PHARMA S.A. (FR) | 2002-03-05 | — | — | US | claimed |
| US-6353108-B1 | 1-(3-PYRIDINYL)-ETHANONE O-((4-METHYLPHENYL) SULPHONYL) OXIME FORMS 3-(2H-AZIRIN-3-YL)-PYRIDINE WHICH IS REACTED WITH ACID AND ALCOHOL TO OBTAIN THE 2,2-DIMETHOXY-2-(3-PYRIDINYL) ETHYL-AMINE WHICH IS REACTED WITH AN AMIDE AND CYCLIZED; INTERMEDIATES ARE NOT ISOLATED | AVENTIS PHARMA S.A. (FR) | 2002-03-05 | — | — | US | disclosed |