Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | MPI | P34949 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3170144 | 1.00 | KDM4E (0.57) | KDM4EKMT2AMEN1EGFRPTGS2 | |
| SCHEMBL212207 | 0.89 | KDM4E (0.71) | KDM4EKMT2AMEN1PTGS2LMNA | |
| SCHEMBL7296406 | 0.83 | MAPT (0.53) | KDM4EKMT2AMEN1PTGS2MAPT | |
| SCHEMBL7296409 | 0.83 | MAPT (0.53) | KDM4EKMT2AMEN1PTGS2MAPT | |
| SCHEMBL31565026 | 0.83 | LMNA (0.46) | KDM4EKMT2AMEN1LMNAMAPT | |
| SCHEMBL92088 | 0.83 | LMNA (0.46) | KDM4EKMT2AMEN1LMNAMAPT | |
| SCHEMBL14395714 | 0.83 | PTGS2 (0.44) | KDM4EKMT2AMEN1EGFRPTGS2 | |
| SCHEMBL11000571 | 0.83 | KDM4E (0.53) | KDM4EKMT2AMEN1EGFRPTGS2 | |
| SCHEMBL27641132 | 0.82 | KDM4E (0.51) | KDM4EKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL10924757 | 0.80 | KDM4E (0.56) | KDM4EKMT2AMEN1EGFRPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095035-B1 | METHOD FOR PREPARING 4-(3-PYRIDINYL)-1H-IMIDAZOLE AND THE INTERMEDIATES USED | AVENTIS PHARMA SA (FR) | 2010-03-17 | — | — | EP | claimed |
| US-20150197503-A1 | PROCESS FOR THE SYNTHESIS OF SUBSTITUTED UREA COMPOUNDS | BIAL PORTELA & Cª S A (PT) | 2015-07-16 | — | — | US | disclosed |
| US-20150197503-A1 | PROCESS FOR THE SYNTHESIS OF SUBSTITUTED UREA COMPOUNDS | BIAL PORTELA & Cª S A (PT) | 2015-07-16 | — | — | US | disclosed |
| EP-1242426-B1 | GAMMA-HYDROXY-2-(FLUOROALKYLAMINOCARBONYL)-1-PIPERAZINEPENTANAMIDES AS HIV PROTEASE INHIBITORS | MERCK & CO INC (US) | 2007-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150197503-A1 | PROCESS FOR THE SYNTHESIS OF SUBSTITUTED UREA COMPOUNDS | REN, F12, HAT1 | KDM4E 1424/4885KMT2A 1061/4885MEN1 2978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.