Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 3/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1157615 | 0.82 | HTT (0.54) | HTTPTGS2TDP1ALDH1A1MAPT | |
| SCHEMBL2076302 | 0.82 | HTT (0.54) | HTTPTGS2TDP1ALDH1A1MAPT | |
| SCHEMBL6313062 | 0.77 | PTGS2 (0.62) | HTTERN1PTGS2TDP1ALDH1A1 | |
| SCHEMBL9687587 | 0.76 | HTT (0.46) | HTTPTGS2TDP1ALDH1A1MAPT | |
| SCHEMBL31706762 | 0.75 | POLB (0.40) | HTTALDH1A1MAPTCYP19A1POLB | |
| SCHEMBL1620299 | 0.74 | ALDH1A1 (0.44) | HTTTDP1ALDH1A1MAPTPKM | |
| SCHEMBL6825987 | 0.74 | HTT (0.59) | HTTTDP1ALDH1A1MAPTLMNA | |
| SCHEMBL62955 | 0.74 | ALDH1A1 (0.50) | HTTTDP1ALDH1A1MAPTLMNA | |
| SCHEMBL6823722 | 0.74 | HTT (0.59) | HTTTDP1ALDH1A1MAPTLMNA | |
| SCHEMBL17132381 | 0.73 | HTT (0.50) | HTTERN1PTGS2TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215558-A1 | COMPOUNDS FOR SPLICING MODULATION | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2025-10-16 | — | — | WO | disclosed |