Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.38 |
| ▸ | SORD | Q00796 | 3/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31706076 | 0.95 | ROCK2 (0.41) | ROCK2KMT2ANPC1RAB9AHRH4 | |
| SCHEMBL31705707 | 0.92 | SORD (0.42) | HRH4HRH3SORDPTGER4KMO | |
| SCHEMBL27457779 | 0.79 | ROCK2 (0.44) | ROCK2HRH4HRH3SORDPTGER4 | |
| SCHEMBL31706338 | 0.76 | HRH3 (0.52) | KMT2AHRH4HRH3SORDKDM4E | |
| SCHEMBL31706298 | 0.76 | HRH3 (0.52) | KMT2AHRH4HRH3SORDKDM4E | |
| SCHEMBL31704767 | 0.75 | CKS1B (0.49) | KMT2ANPC1RAB9AHRH4HRH3 | |
| SCHEMBL31705275 | 0.74 | CKS1B (0.48) | NPC1RAB9ATRPV1KDM4EALDH1A1 | |
| SCHEMBL31705550 | 0.74 | CKS1B (0.48) | NPC1RAB9ATRPV1KDM4EALDH1A1 | |
| SCHEMBL21880062 | 0.74 | KMO (0.53) | HRH4HRH3SORDALDH1A1KMO | |
| SCHEMBL27457780 | 0.73 | PTGER4 (0.45) | ROCK2HRH4HRH3SORDPTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |