Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 2/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | KRAS | P01116 | 3/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31709387 | 0.89 | ALDH1A1 (0.43) | ALDH1A1KDM4ECDK1CCNB2CCNB1 | |
| SCHEMBL16262449 | 0.82 | ALDH1A1 (0.48) | ALDH1A1CDK1CCNB2CCNB1GSK3B | |
| SCHEMBL5418830 | 0.79 | CCNB2 (0.44) | ALDH1A1KDM4ESMN1; SMN2CDK1CCNB2 | |
| SCHEMBL639520 | 0.79 | LMNA (0.46) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL641720 | 0.79 | GABRG2 (0.45) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL28635974 | 0.78 | ALDH1A1 (0.44) | ALDH1A1CDK1CCNB2CCNB1GSK3B | |
| SCHEMBL31710152 | 0.76 | LMNA (0.48) | ALDH1A1KDM4ESMN1; SMN2CDK1CCNB2 | |
| SCHEMBL24093939 | 0.73 | MEN1 (0.44) | MEN1KMT2A | |
| SCHEMBL25230511 | 0.72 | ALDH1A1 (0.68) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL23997383 | 0.72 | L3MBTL1 (0.49) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250325677-A1 | STAT6 DEGRADERS | GILEAD SCIENCES INC (US) | 2025-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250325677-A1 | STAT6 DEGRADERS | STAT6, STAT5B, STAT1 | ALDH1A1 959/4885KDM4E 167/4885SMN1; SMN2 3259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.