Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13799191 | 1.00 | MMP8 (0.41) | MMP8NPY1RNPY2RABCB1ELANE | |
| SCHEMBL14465126 | 0.89 | MMP8 (0.43) | MMP8NPY1RNPY2RELANEHPRT1 | |
| SCHEMBL3161587 | 0.84 | ITGA4 (0.42) | MMP8CTSLCTSBCTSSCTSK | |
| SCHEMBL13799190 | 0.81 | ALDH1A1 (0.38) | MMP8NPY1RNPY2RABCB1POLB | |
| SCHEMBL4092235 | 0.81 | ALDH1A1 (0.38) | MMP8NPY1RNPY2RABCB1POLB | |
| SCHEMBL3162028 | 0.78 | MMP8 (0.40) | MMP8ELANETP53OPRK1EPHX2 | |
| SCHEMBL4092431 | 0.75 | MMP13 (0.39) | MMP8POLBGAAALDH1A1 | |
| SCHEMBL30688463 | 0.75 | MMP9 (0.48) | MMP8MMP9MMP14ALDH1A1 | |
| SCHEMBL4765072 | 0.75 | MMP8 (0.59) | MMP8NPY1RNPY2RELANEHPRT1 | |
| SCHEMBL6322057 | 0.75 | MMP8 (0.59) | MMP8NPY1RNPY2RELANEHPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101374820-B | Piperazine compounds with a herbicidal action | BASF SE | 2013-09-04 | — | — | CN | disclosed |
| US-8450301-B2 | Piperazine compounds with a herbicidal action | BASF SE (DE) | 2013-05-28 | — | — | US | disclosed |
| EP-1971580-B1 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | BASF SE (DE) | 2010-02-24 | — | — | EP | disclosed |
| US-20090156553-A1 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | BASF SE (DE) | 2009-06-18 | — | — | US | disclosed |
| CN-101374820-A | Piperazine compounds with a herbicidal action | BASF SE (DE) | 2009-02-25 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156553-A1 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | DDT, CAT, CIP2A | MMP8 2825/4885NPY1R 2590/4885NPY2R 2316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.