SCHEMBL31720948

SCHEMBL31720948

Cn1c(-c2ccc(NC(=O)c3ccc([N+](=O)[O-])cc3)cc2)nc2ccc(NC(=O)c3ccc([N+](=O)[O-])cc3)cc21

nearest known ligand 0.64

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ PPARG P37231 2/20 0.64
▸ RAB9A P51151 5/20 0.59
▸ MAPT P10636 5/20 0.58
▸ MMP2 P08253 3/20 0.57
▸ MMP9 P14780 3/20 0.57
▸ MMP8 P22894 3/20 0.57
▸ MMP13 P45452 3/20 0.57
▸ ALDH1A1 P00352 1/20 0.56
▸ PKM P14618 1/20 0.56
▸ RXFP1 Q9HBX9 1/20 0.56
▸ KMT2A Q03164 4/20 0.54
▸ NPC1 O15118 2/20 0.54
▸ MEN1 O00255 3/20 0.54
▸ POLB P06746 3/20 0.52
▸ PRSS12 P56730 1/20 0.51
▸ PIN1 Q13526 1/20 0.49
▸ TP53 P04637 1/20 0.49
▸ MITF O75030 2/20 0.49
▸ MAPK1 P28482 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13783492 0.82 RAB9A (0.53) PPARGRAB9AMAPTMMP2MMP9
SCHEMBL12325432 0.81 MMP2 (0.58) PPARGRAB9AMAPTMMP2MMP9
SCHEMBL31720872 0.81 NAMPT (0.58) RAB9AMAPTKMT2ANPC1MEN1
SCHEMBL26603124 0.81 NAMPT (0.58) RAB9AMAPTKMT2ANPC1MEN1
SCHEMBL13844317 0.81 MMP2 (0.52) PPARGRAB9AMAPTMMP2MMP9
SCHEMBL14922009 0.81 MMP2 (0.52) PPARGRAB9AMAPTMMP2MMP9
SCHEMBL15223763 0.80 PRSS12 (0.52) PPARGRAB9AMAPTALDH1A1PKM
SCHEMBL13844332 0.79 PIN1 (0.54) PPARGRAB9AMAPTMMP2MMP9
SCHEMBL13844326 0.79 MMP2 (0.51) PPARGRAB9AMAPTMMP2MMP9
SCHEMBL28958918 0.79 RAB9A (0.62) PPARGRAB9AMAPTALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250339494-A1 COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS UNIV PARIS CITE (FR) 2025-11-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250339494-A1 COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS IL2, CXCL10, IFNG PPARG 1992/4885RAB9A 1672/4885MAPT 2956/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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