Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 12/20 | 0.38 |
| ▸ | PGR | P06401 | 7/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | AGER | Q15109 | 1/20 | 0.34 |
| ▸ | POLQ | O75417 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24313926 | 0.89 | MCL1 (0.42) | MCL1ARPGRHSD17B3KDM4E | |
| SCHEMBL29587761 | 0.89 | MCL1 (0.42) | MCL1ARPGRHSD17B3KDM4E | |
| SCHEMBL31723087 | 0.81 | PPP5C (0.33) | — | |
| SCHEMBL31723088 | 0.81 | PPP5C (0.33) | — | |
| SCHEMBL24313796 | 0.76 | RBP4 (0.42) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL24313801 | 0.75 | RAB9A (0.36) | MCL1ARHSD17B3KDM4EMEN1 | |
| SCHEMBL31723070 | 0.75 | CYP2C9 (0.31) | — | |
| SCHEMBL31723096 | 0.75 | PDE4D (0.34) | — | |
| SCHEMBL30538372 | 0.73 | MCL1 (0.40) | MCL1ARPGRHSD17B3KDM4E | |
| SCHEMBL24314320 | 0.72 | SCN9A (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4229045-B1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | BROAD INST INC (US) | 2025-11-12 | — | — | EP | claimed |